This session presents cutting-edge research and field applications focused on enhancing the integrity, reliability, and monitoring of subsea pipeline systems under demanding offshore environments. Papers highlight the qualification and long-term performance of advanced materials and designs demonstrating the evolution of corrosion-resistant solutions through data-driven qualification and decades of operational experience. Contributions also address critical challenges in maintaining pipeline integrity, from root-cause analysis of severe corrosion to experimental methods assessing the structural performance of flexible pipes exposed to high CO2 concentrations. Novel approaches, such as DNV’s Finally, innovative surface treatments based on nanocomposite coatings are presented for field validation, offering enhanced corrosion mitigation and flow assurance performance in high-risk flowlines.